It’s ancient knowledge that a spoonful of turmeric can soothe inflammation, but now a UA scientist is exploring how the complex structure of natural plants long used in Asia can offer medicinal benefits in other ways, many of them unnoticed in the West.
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For years, biomedical science has been turning individual genes on and off as way to treat gene-based maladies, and as a research tool. Now, a new challenge involves finding ways to bring the entire genetic blueprint of humans, animals and plants into play.
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Devices that spin off from the research of a UA bioengineer may one day protect airports and border checkpoints, enhance the work of pharmaceutical companies and speed the tests of water quality around the world. On a battlefield, her instant blood test for H.I.V. and hepatitis could hasten a direct transfusion and save a soldier’s life. Her device to test for signs of life in extreme environments like outer space could help NASA search for extraterrestrial life. Linda Powers, a UA bioengineer and BIO5 member, has done such projects and many more in the field of medical diagnostics.
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For most bioscientists, a slice of Nobel Prize fame would be a very big deal. For the UA’s Tom Doetschman, it is minor compared to his new goal: helping prevent colon cancer. Asked about his role in the 2007 Nobel Prize, Doetschman says drily, “I got mentioned.” Then he adds, “Those were heady days.” But these days, he has high hopes for the UA’s “knockout mouse” program, which he founded and which has already achieved global prominence in the field that was honored with that Nobel Prize in medicine. It is a UA core facility, called Genetically Engineered Mouse Models, or GEMM Core.
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Up close, a thin slice of a human cell wall might look like the Great Wall of China, with an array of towers, tubes and molecular mailboxes. Getting a message through is tricky. The molecule must hit the right receptor, a kind of smart mailbox that regulates life, screening messages, letting only a few bind to the cell.
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